This technology had been used in 30m~3 fermenters. The potency and fer-mentation index of spiramycin were increased 30.2% and 18.9%,respectively.

• 在30 m~3发酵罐上应用该工艺；发酵效价与原工艺比较可提高30%25；发酵指数提高18.；9%25。