This study was to define the maximal tolerant dose (MTD) of paclitaxel in weekly paclitaxel with concurrent intensity-modulated radiotherapy (IMRT) for local-regionally advanced NPC.

• 本研究的目的在于确定每周1次紫杉醇与调强适形放射治疗(intensity modulated radiation therapy,IMRT)同期使用,治疗局部晚期鼻咽癌患者中紫杉醇的最大耐受剂量(maximal tolerant dose,MTD)。