This study was done to establish a human lung adenocarcinoma cell line SPC-A1 with the characterization of docetaxel resistance, to investigate its biological mechanism of drug resistance and how to reverse the resistance.

• 本研究拟通过体外诱导耐药建立肺癌SPC-A1的多西他赛耐药细胞系,以便于进一步研究其耐药机制及耐药逆转。