This review describes the origin and precise location of HSC in the embryo and in AGM region, the hematopoietic microenviroment and the hemato- poietic regulatory mechanisms in AGM region.

• 本文综述了有关造血干细胞在胚胎和AGM区中的起源与定位 ,AGM区造血微环境以及其中的分子调控机制等问题。