This paper texted the process to prepare metadoxine from vitamine B6 hydrochloric acid salt ,pyroglutamic acid and isoproanol.Pure content is 96.3%.

• 本文以维生素B6氯化氢盐、焦谷氨酸和异丙醇为原料；固相合成美他多辛；纯度达96.；3%25。