This enhancing activity of lipase might be attributed to the structural changes of the stratum corneum by some special biochemical reactions of lipase to lipids.

• 胰脂肪酶可能直接作用于角质层脂质部分，通过某种特异的生物化学反应，使其构造疏松或变为无序状态，从而促进药物的透皮吸收。