This article reviews the epidemiology and pathophysiology of migraine headache and patent foramen ovale(PFO),and the impact of PFO closure on migraine.

• 回顾偏头痛和卵圆孔未闭的发病情况和病理生理学机制,以及经导管封堵卵圆孔未闭对偏头痛的影响,评价其应用价值。