They found that increased ceramide leels are a requirement of impaired insulin response in mice gien a glucocorticoid used to treat rheumatoid arthritis.

• 他们发现对给糖皮质激素用于治疗类风湿性关节炎的老鼠来说，要破坏胰岛素反应就必须增加体内神经酰胺浓度。