They also found AMD3100 had significant antitumor activity through regulating pathways downstream of CXCR4 and impaired formation of tumor micro vessels and expression of invasive associated genes.

• 他们也发现AMD3100通过调节CXCR4下游通路和损害肿瘤微血管构造以及浸润性相关基因的表达，具有重要的抗肿瘤活性。