These receptors act as on-off switch; when the right molecule (in this case oestrogen or progesterone) binds to its specific receptor, the switch is turned on, leading, in the case of breast cancer, to disease progression.

• 这些受体的作用类似于开关；当正确的分子（这里指雌二醇或孕酮）和其特异的受体结合时，这个开关就打开，导致乳癌的进展。