Therefore it indicated that BPO-1 has an obvious apoptosis inducing effect on the human gastric adenocarcinoma cells by regulating the expression of oncogenes and tumor suppressors genes such as mutant p53, bcl-2, c-myc, Fas, p21 WAFI/C1P1 and p16 genes.

• 其诱导癌细胞作用机理与调节和干预bcl-2、 c-myc等癌基因、p53、 p16、 p21~WAFI/CIPI等抑癌基因的表达有关。