There existed the expression of ET 1 mRNA and its receptors (ET A R mRNA and ET B R mRNA), and also the synthesis of ET 1 peptide in renal tubular epithelial cell.

• 肾小管上皮细胞既有ET?1mRNA的表达，又有ET的两种受体（ETA?RmRNA和ETB?RmRNA）的表达，还有ET?1的蛋白合成及分泌。