Then we chose the highly invasive MDA-MB-435 cell and the low invasive MCF-7 for further investigating the silence mechanism of TFPI-2 during the development of breast cancer.

• 在已检测的各种细胞中，TFPI-2 的mRNA水平与与蛋白水平相符。根据这些结果，我们选取高侵袭的乳腺癌细胞株MDA-MB-435和低侵袭的乳腺癌细胞株MCF-7为模型，进行TFPI-2表达下调的机制研究。