The work of Ernst Mayr, a proponent of idea that the founder effect could give rise to new lineages of species, lends support to the Wright model.

• 一个群体不可能从等位基因的随机洗牌改组中获得新的等位基因传递给下一代，但这种洗牌改组可能会导致现有的等位基因消失。