The water content of brain was measured by wet-dry weight formula and Evans blue(EB) concentration was detected after intravenous injection(3 mg/kg) after 2,7 and 30 days post irradiation in each group.

• 分别于照射后2、7和30d采用脑干-湿重法检测脑含水量,并用单次静脉注射3mg/kg伊文氏蓝(EB)后脑组织的EB含量法评估BBB破坏情况。