The trypsin was covalently linked with chemical modified granule chitosan and was used to isolate and purify aprotininum from the extract of cattle lungs by affinity chromatography.

• 采用琼脂糖凝胶为载体,共价偶联牛胰蛋白酶,制成抑肽酶亲和吸附剂,将其用于亲和层析牛肺提取液,分离纯化高比活抑肽酶。