The true cause of SARS appears to be a novel coronavirus,SARS-associated coronavirus(SARS-CoV)with some unusual properties that can result in progressive respiratory failure due to alveolar damage.

• 中性粒细胞在肺部的聚集与活化,从而释放大量弹性蛋白酶,损伤肺部微血管和表面活性物质,可能是冠状病毒感染后引起急性肺损伤的重要病理生理机制。