The three agents were highly active against Enterobacteriaceae, and they also possessed good antimicrobial activity against P.aeruginosa, Acinetobacter spp and E.faecalis.

• 帕尼培南与亚胺培南体外抗菌作用相仿，两者对肺炎克雷伯氏菌、肠杆菌属等革兰氏阴性菌作用略逊于美罗培南。