The thesis here described the chiral resolution of Betti Base and the synthesis of their derivatives, as well as their applications as chiral ligands in asymmetric synthesis.

• 本文选择了Betti碱及其手性衍生物为研究目标，完成了Betti碱的拆分、手性配体结构的合成，以及它们在催化不对称合成中的初步应用。