The synergistic effects of LPS, BLP and bacterial DNA were further examined in vitro at the level of PRRs on the cell surface of effector cells using cultured primary alveolar macrophages.

• 通过体外实验,从效应细胞表面病原菌相关模式识别受体(CD14、TLR4、TLR2、TLR9)水平进一步观察了细菌LPS、BLP和CpG-ODN对天然免疫细胞的协同刺激效应及其可能机制。