The study is based on HLA-A2 restricted CTL epitope of tumor associated antigen HER2/neu and regional chiral peptides D-P42-50, D-P782-790 was first designed and synthesised.

• 本研究以肿瘤相关抗原HER2/neu蛋白的HLA-A2限制性CTL表位为基础，首次设计并合成了具有局部手性特征的多肽D-P42-50，D-P782-790 。