The specific niches within it may provide a sanctuary for subpopulations tumor cells that affords a survival advantage following initial drug exposure and may promote acquired drug resistance.

• 肿瘤微环境中特殊的生态位可能为肿瘤细胞亚群提供了一个“避难所”，即在最初暴露于化疗药物之后提供了一种生存优势，它促进了肿瘤获得性耐药的发生。