The secondary structure of a staphylokinase variant(K35R,DGR) encapsulated in poly(lactic-co-glycolic acid)((PLGA)) microspheres was quantitatively examined by Fourier transform infrared(FTIR) spectroscopy.

• 用复乳溶剂挥发法制备了葡激酶突变体(K35R,DGR)的PLGA微球,并用傅里叶变换红外光谱法(FTIR)定量研究了PLGA微球内DGR的二级结构。