The second-generation Brush-Type CSP (DNB-Leucine CSP) had been researched in this thesis, including the synthesis of DNB-Leucine CSP and the column packing for analytical and preparative scales.

• 本论文选择了第二代刷型手性固定相DNB-Leucine CSP作为研究对象,从DNB-Leucine CSP的合成、DNB-Leucine CSP分析柱和制备柱的填装、分析柱和制备柱柱效的测定等方面,作了深入的研究,并且对实验结果和实验机理做了探讨。