The results suggest that agmatine may inhibit morphine abstinence syndrome,the possible mechanisms include activation of imidazoline receptors,prevention of cAMP up-regulation and over-shooting,and inhibition of NOS activity.

• 胍丁胺可抑制吗啡的戒断症状,其可能的机制是通过激活咪唑啉受体抑制cAMP的上调和戒断时的超射及抑制NOS的活性。