The results showed that ED50, LD50of the QMB combination (small white mice i.p.) were 13.15 mg/kg, 67.676 mg/kg body weight and Al were 5.146, respectively. The results indicate that the Al is far more higher than usual demand (3).

• 通过序贯法进行急性毒性试验，测定QMB合剂小白鼠腹腔注射（ip）半数有效量ED_(50)为13.；15mg/kg体重，半数致死量LD_(50)为67