The research of liposome, a new kind of drug formulation, is hot in this field, because liposome has the ability of entrapping drugs and a good permeability into biomembrane such as cell membrane.

• 本论文采用超临界法制备盐酸小檗碱脂质体，考察不同乙醇浓度下脂质体的包封率和稳定性，完善了脂质体制备的最佳条件。