The production of Ganoderma lucidum by submerged culture using Coix lachryma-jobi as substrate was studied,and the medium was optimized by response surface methodology(RSM).

• 研究了以薏苡仁为基质的灵芝液体发酵,并用响应面分析法对培养基进行了优化,结果表明：薏苡仁油可促进灵芝菌解体的生长及胞外多糖的生产,最适加入量为1。