The present study showed that EsA could lower the high level of anti-ds DNA antibody and inhibit the hyperactivity of T and B cells in a dose-dependent manner.

• EsA作用于模型小鼠后，发现EsA能够剂量依赖性地降低模型小鼠高水平的抗ds-DNA抗体及抑制T、B细胞的过度增殖。