The preparation method and the application of diethoxy methane (DEM) were summarized in this paper.The recent methods of separating DEM from ethanol aqueous solution were reviewed in the paper.

• 本文综述了二乙氧基甲烷(DEM)的制备方法以及在有机合成中的应用，总结了国内外分离DEM乙醇水溶液的方法。