The prealence of Noonan syndrome has not been determined accurately to date, but most authors report 1 in 1,000 - 2,500 lie births, affecting males and females equally.

• 直至今日，努南综合症的患病率尚未准确测得，但大多数作者的报告是在1000到2500名活产儿中即有一例，男女患病机率相等。