The positive expressions of P16 in glioma cell line TJ905 was transmitted and colony formation of tumor cells was greatly inhibited by recombinant adenovirus, after 6 days the inhibitory rate of the growth of tumor cells was 98%.

• 重组体腺病毒能介导P16外源基因在恶性脑胶质瘤细胞系TJ905细胞中阳性表达,6天时肿瘤细胞生长抑制率为98%25,并且能显著地抑制肿瘤细胞的克隆形成能力。