The pharmacokinetics of encainide(ENC)was studied in rats afterpo. The serum concentrations of ENC were determined by HPLC method.

• 采用 HPLC 法测定大鼠血清中的恩卡胺浓度,研究了不同剂量恩卡胺一次灌胃后在大鼠体内的药物动力学。