The patients of DN with hypertension were used angiotensin converting enzyme inhibitors(ACEI) or angiotensin receptor blockers(ARB) treatment and pioglitazone 15mg/d,12 weeks.

• 在常规降糖、有高血压者应用血管紧张素转换酶抑制剂(ACEI)或血管紧张素受体阻滞剂(ARB)降压的基础上,治疗组加用吡格列酮15mg/d口服,连用12周。