The outer-approximation method is generalized by replac-ing the supporting functions of the original nonlinear functions with Lagrangian dual functions and a mixee-integer nonlinear programming(MINLP)global optimization method is proposed in this paper.

• 本文应用Lagrange对耦函数作为外部近似函数，对外部近似法进行了推广，从而建立了一个求解过程工程系统设计中混合整数非线性规划（MINLP）问题的整体最优化方法。