The order of the specificity was RF +AKA+ anti-CCP antibody >AKA+ anti-CCP antibody > RF. The sensitivity and specificity of RF+AKA+antiCCP antibody were significantly higher than that in any single test.

• 对RA诊断的特异性为RF+AKA+抗CCP抗体>AKA+抗CCP>RF；其中三者联检特异性明显高于其它组(P<0.；05)。