The optimal conditions were obtained by central composite designs and response surface analysis as follows: peptone 22.14 g/L, Jerusalem artichoke 117.28mL, (NH4)2HPO43.94 g/L, NaCl5.0 g/L, MgSO40.50 g/L, MnSO40.10 g/L.

• 采用中心组合设计和响应法对宇佐美曲霉培养条件进行优化；得到优化培养基为:蛋白胨22.；14 g/L；菊芋汁117