The oncoprotein encoded by E7 gene is considered as ideal specific antigen against HPV associated cancer. The E7 oncoprotein is characterized by several linear B cell epitope, CD4+T cell epitope and CD8+ cell epitope.

• 由HPVl6E7基因产生的早期蛋白E7与细胞的转化和恶性变密切相关，并且被认为是HPV相关肿瘤特异性肿瘤排斥抗原，含有多个线性B细胞表位、CD4+T细胞表位和CD8+CTL表位。