The now-required Boxed Warning will highlight the risk of bacterial sepsis, viral meningitis, invasive fungal disease, progressive multifocal leukoencephalopathy and other opportunistic infections.

• 现在提出的严重警告将突出细菌感染、病毒性脑膜炎、侵袭性真菌病、渐进多灶性白质脑病和其他可能出现的感染的危险。