The mouse can accept the biggest physical volume that is 0.4ml/10g(40ml/kg), so it was the biggest dosage (maximum dosage) of the decoction to infuse about 80g/kg.

• 1 急性毒性验:将热痹颗粒方药煎煮浓缩至浓度为200%25；小鼠一次灌胃可接受最大体积为0.；4ml/10g(即40ml/kg)；故一次灌胃剂量按最大可给药剂量(最大耐受量)80g/kg给予。