The metabolism of diphenytriazol was investigated in five kinds of rat liver microsomal incubate pretreated with phenobarbital (PB), dexamethasone (Dex), p-naphthoflavone (BNF), diphenytriazol and control.
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方法:l)用CYPIA、CYPZB的两种特征性底物乙氧基异吩恶吟与7一戊氧基异吩恶吟在经不同天数地非三吟处理的鼠肝微粒体中代谢,用荧光仪在激发波长(ex)565nm,发射波长(em)587nln下直接测定代谢物异吩恶吟的生成量。
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