The mechanisms of opiate dependence may include reward center,mesolimbic DA pathway,opiod receptor and endogenous opiod.Other transmitter system may also be involved in the mechanisms.

• 阿片为罂粟中的主要成分,阿片依赖性机制可能涉及脑内奖赏中心、多巴胺(DA)通路、阿片受体及内源性阿片肽及多种神经递质系统。