The mechanism of depressor effect of AHF may be related to the inhibitory effects on calcium uptake of vascular smooth muscle, especially of resistance vessel smooth muscle.

• 以上结果表明:EHS红细胞中存在AHF,能显著降低高血压大鼠血压,其降压机制可能与其抑制VSM特别是小动脉VSM Ca~(2+)内流有关。