The mechanism may be related with increasing SOD activity and enhancing the antioxidation property and stabilizing the cell transmembrane potential of cardiac muscle.

• 结论：黄连素预处理对大鼠心肌缺血再灌注损伤具有保护作用，其机制可能与增加SOD活性、增强心肌抗氧化能力、稳定心肌细胞膜电位有关。