The measurement of urinary NTx and serum ICTP are of significant utility as biochemical markers of bone metastasis in patients with malignant carcinoma and can be used to achieve a timely diagnosis for bone metastasis of the malignant tumor.

• NTx和血ICTP对恶性肿瘤患者骨转移的诊断有重要的参考意义,可协助及时诊断恶性肿瘤骨转移。