The main mechanism of ketoconazole for the highly selective interference with fungal cytochrome P-450 activity, thus inhibiting ergosterol on fungal cell membrane biosynthesis.

• 酮康唑的作用机制主要为高度选择性干扰真菌的细胞色素P-450的活性，从而抑制真菌细胞膜上麦角固醇的生物合成。