The kidneys are injured when renal perfusion is critically reduced, leading to acute tubular necrosis and renal insufficiency manifested by oliguria and progressive rise in serum creatinine.

• 肾灌注严重减少则伤肾,导致急性肾小管坏死和肾机能不全,表现为少尿和血清肌酸酐的不断上升。