The internality with(or) acquired character of tumor cell cause to chemotherapy failure.To explore an individuation chemotherapy project,is the hot and difficult spots of clinical research at present.

• 肿瘤细胞的内在和(或)获得性多药耐药是导致肿瘤患者化疗失败的主要原因,寻求个体化化疗方案,是目前临床研究中的热点和难点。