The eukaryotic regulating expression system Tet-Off has Potentiality in gene therapy on the neurodegenerative disorders of CNS, such as AD, when using hNT-3 or other genes.

• 在应用hNT-3进行AD等中枢神经退行性疾病的基因治疗中，Tet-off调控表达系统具有潜在的应用前景。