The effect of tetramethylprazine on histamine and 5-HT were analyzed by in-vitro ileum contraction test in guinea pigs.

• 结果川芎嗪能显著降低大鼠炎性渗出物中组胺、5-羟色胺的含量,显著拮抗组胺、5-羟色胺所致豚鼠离体回肠的收缩。